Expression of GBGT1 is epigenetically regulated by DNA methylation in ovarian cancer cells

BACKGROUND: The GBGT1 gene encodes the globoside alpha-1,3-N-acetylgalactosaminyltransferase 1. This enzyme catalyzes the last step in the multi-step biosynthesis of the Forssman (Fs) antigen, a pentaglycosyl ceramide of the globo series glycosphingolipids. While differential GBGT1 mRNA expression h...

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Detaylı Bibliyografya
Asıl Yazarlar: Jacob, Francis, Hitchins, Megan P, Fedier, André, Brennan, Kevin, Nixdorf, Sheri, Hacker, Neville F, Ward, Robyn, Heinzelmann-Schwarz, Viola A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193910/
https://ncbi.nlm.nih.gov/pubmed/25294702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-15-24
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