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Association of ITPA Genotype with Event-Free Survival and Relapse Rates in Children with Acute Lymphoblastic Leukemia Undergoing Maintenance Therapy

Although the treatment of acute lymphoblastic leukemia (ALL) has improved significantly over recent decades, failure due to treatment-related toxicities and relapse of the disease still occur in about 20% of patients. This retrospective study included 308 pediatric ALL patients undergoing maintenanc...

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Bibliographische Detailangaben
Hauptverfasser: Smid, Alenka, Karas-Kuzelicki, Natasa, Milek, Miha, Jazbec, Janez, Mlinaric-Rascan, Irena
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193781/
https://ncbi.nlm.nih.gov/pubmed/25303517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109551
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