Inhibition of Tyrosine Kinase Receptor Tie2 Reverts HCV-Induced Hepatic Stellate Cell Activation

BACKGROUND: Hepatitis C virus (HCV) infection is a major cause of chronic liver disease (CLD) and is frequently linked to intrahepatic microvascular disorders. Activation of hepatic stellate cells (HSC) is a central event in liver damage, due to their contribution to hepatic renewal and to the devel...

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Autori principali: Martín-Vílchez, Samuel, Rodríguez-Muñoz, Yolanda, López-Rodríguez, Rosario, Hernández-Bartolomé, Ángel, Borque-Iñurrita, María Jesús, Molina-Jiménez, Francisca, García-Buey, Luisa, Moreno-Otero, Ricardo, Sanz-Cameno, Paloma
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193738/
https://ncbi.nlm.nih.gov/pubmed/25302785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106958
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