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Generation of Functional, Antigen-Specific CD8+ Human T Cells from Cord-Blood Stem Cells using Exogenous Notch and Tetramer-TcR Signaling
In vitro differentiation of mouse and human stem cells into early T cells has been successfully demonstrated using artificial Notch signaling systems. However, generation of mature, antigen-specific, functional T cells, directly from human stem cells has remained elusive, except when using stromal c...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4193361/ https://ncbi.nlm.nih.gov/pubmed/23939944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1512 |
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