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Intratumoral heterogeneity in kidney cancer
Clear cell renal cell carcinoma (CCRCC) is characterized by mutation of the VHL gene and loss of a segment of chromosome 3. A new study using multi-region exome sequencing has identified substantial intratumoral heterogeneity within large primary CCRCCs, which has profound implications for understan...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4193312/ https://ncbi.nlm.nih.gov/pubmed/24569233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2904 |
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