Serum amyloid P component prevents proteolysis of the amyloid fibrils of Alzheimer disease and systemic amyloidosis.

Extracellular deposition of amyloid fibrils is responsible for the pathology in the systemic amyloidoses and probably also in Alzheimer disease [Haass, C. & Selkoe, D. J. (1993) Cell 75, 1039-1042] and type II diabetes mellitus [Lorenzo, A., Razzaboni, B., Weir, G. C. & Yankner, B. A. (1994) Nature...

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Bibliografiska uppgifter

I publikationen:	Proc Natl Acad Sci U S A
Huvudupphov:	Tennent, G A, Lovat, L B, Pepys, M B
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	National Academy of Sciences 1995
Ämnen:	Research Article
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41931/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7753801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.10.4299
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