A Novel Long-Acting Glucagon-Like Peptide-1 Agonist with Improved Efficacy in Insulin Secretion and β-Cell Growth

BACKGROUND: Glucagon-like peptide-1 (GLP-1) is an incretin hormone produced by cleavage of proglucagon in intestinal L-cells. In the pancreas, GLP-1 stimulates post-prandial insulin secretion, promotes insulin biosynthesis, and improves insulin sensitivity. Because of its insulinotropic activity, GL...

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Hlavní autoři: Kim, Hee Young, Hwang, Jong-Ik, Moon, Mi Jin, Seong, Jae Young
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Endocrine Society 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192806/
https://ncbi.nlm.nih.gov/pubmed/25309791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3803/EnM.2014.29.3.320
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