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Molecular and clinical predictors of inhibitor risk and its prevention and treatment in mild hemophilia A

The risk for inhibitor development in mild hemophilia A (factor VIII levels between 5 and 40 U/dL) is larger than previously anticipated, continues throughout life, and is particularly associated with certain mutations in F8. Desmopressin may reduce inhibitor risk by avoiding exposure to FVIII conce...

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書目詳細資料
Main Authors: Castaman, Giancarlo, Fijnvandraat, Karin
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192746/
https://ncbi.nlm.nih.gov/pubmed/25139352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-546127
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