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Molecular and clinical predictors of inhibitor risk and its prevention and treatment in mild hemophilia A
The risk for inhibitor development in mild hemophilia A (factor VIII levels between 5 and 40 U/dL) is larger than previously anticipated, continues throughout life, and is particularly associated with certain mutations in F8. Desmopressin may reduce inhibitor risk by avoiding exposure to FVIII conce...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4192746/ https://ncbi.nlm.nih.gov/pubmed/25139352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-546127 |
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