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Molecular and clinical predictors of inhibitor risk and its prevention and treatment in mild hemophilia A

The risk for inhibitor development in mild hemophilia A (factor VIII levels between 5 and 40 U/dL) is larger than previously anticipated, continues throughout life, and is particularly associated with certain mutations in F8. Desmopressin may reduce inhibitor risk by avoiding exposure to FVIII conce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Castaman, Giancarlo, Fijnvandraat, Karin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192746/
https://ncbi.nlm.nih.gov/pubmed/25139352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-546127
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