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Structural model of ubiquitin transfer onto an artificial RING finger as an E3 ligase

The artificial WSTF PHD_EL5 RING finger was designed via “α-helical region substitution”, and its structural model for the attachment of activated ubiquitin has been demonstrated. Chemical modifications of Cys residues, the circular dichroism spectra, and substrate-independent ubiquitination assays...

詳細記述

保存先:
書誌詳細
第一著者: Miyamoto, Kazuhide
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192618/
https://ncbi.nlm.nih.gov/pubmed/25300604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06574
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