Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling

Sorting nexins (SNXs) or phox homology (PX) domain containing proteins are central regulators of cell trafficking and signaling. A subfamily of PX domain proteins possesses two unique PX-associated domains, as well as a regulator of G protein-coupled receptor signaling (RGS) domain that attenuates G...

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Bibliographic Details
Main Authors: Mas, Caroline, Norwood, Suzanne J., Bugarcic, Andrea, Kinna, Genevieve, Leneva, Natalya, Kovtun, Oleksiy, Ghai, Rajesh, Ona Yanez, Lorena E., Davis, Jasmine L., Teasdale, Rohan D., Collins, Brett M.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192506/
https://ncbi.nlm.nih.gov/pubmed/25148684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.595959
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