MR Cholangiography Demonstrates Unsuspected Rapid Biliary Clearance of Nanoparticles in Rodents: Implications for Clinical Translation

Due to their small size, lower cost, short reproduction cycle, and genetic manipulation, rodents have been widely used to test the safety and efficacy for pharmaceutical development in human disease. In this report, MRI cholangiography demonstrated an unexpected rapid (<5 min) biliary elimination...

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Autors principals: Bulte, Jeff W.M., Schmieder, Anne H., Keupp, Jochen, Caruthers, Shelton D., Wickline, Samuel A., Lanza, Gregory M.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192078/
https://ncbi.nlm.nih.gov/pubmed/24832959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2014.05.001
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