Radiation Dosimetry and Biodistribution of the Translocator Protein Radiotracer [(11)C]DAA1106 Determined with PET/CT in Healthy Human Volunteers

INTRODUCTION: When microglia become activated (an integral part of neuroinflammation), cellular morphology changes and expression of translocator protein (TSPO) 18 kDa is increased. Over the past several years, [(11)C]DAA1106 has emerged as a reliable radiotracer for labeling TSPO with high affinity...

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Detalhes bibliográficos
Main Authors: Brody, Arthur L., Okita, Kyoji, Shieh, Jennifer, Liang, Lidia, Hubert, Robert, Mamoun, Michael, Farahi, Judah, Mandelkern, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192057/
https://ncbi.nlm.nih.gov/pubmed/25156039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2014.07.004
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