Humanized Staphylococcal Enterotoxin B (SEB)–Specific Monoclonal Antibodies Protect From SEB Intoxication and Staphylococcus aureus Infections Alone or as Adjunctive Therapy With Vancomycin

Background. Staphylococcal enterotoxin B (SEB), a potential biological warfare agent, is a potent superantigen that contributes to the virulence of methicillin-resistant Staphylococcus aureus (MRSA), which is a major health threat in the United States. Efforts to develop toxin-neutralizing antibodie...

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Detalhes bibliográficos
Main Authors: Varshney, Avanish K., Wang, Xiaobo, MacIntyre, Jennifer, Zollner, Richard S., Kelleher, Kerry, Kovalenko, Oleg V., Pechuan, Ximo, Byrne, Fergus R., Fries, Bettina C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192055/
https://ncbi.nlm.nih.gov/pubmed/24803533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu198
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