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Quantitative proteome profiling of lymph node positive vs. negative colorectal carcinomas pinpoints MX1 as a marker for lymph node metastasis

We used high-resolution mass spectrometry to measure the abundance of more than 9,000 proteins in 19 individually dissected colorectal tumors representing lymph node metastatic (n=10) and non-metastatic (n=9) phenotypes. Statistical analysis identified MX1 and several other proteins as overexpressed...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Croner, Roland S., Stürzl, Michael, Rau, Tilman, Metodieva, Gergana, Geppert, Carol I., Naschberger, Elisabeth, Lausen, Berthold, Metodiev, Metodi V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192020/
https://ncbi.nlm.nih.gov/pubmed/24771638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28929
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