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Nuclear Receptor Modulation - Role of Coregulators in Selective Estrogen Receptor Modulator (SERM) Actions

Selective Estrogen Receptor Modulators (SERMs) are a class of small-molecule chemical compounds that bind to estrogen receptor (ER) ligand binding domain (LBD) with high affinity and selectively modulate ER transcriptional activity in a cell- and tissue-dependent manner. The prototype of SERMs is ta...

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Autors principals: Feng, Qin, O’Malley, Bert W.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192004/
https://ncbi.nlm.nih.gov/pubmed/24945111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2014.06.008
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