Sildenafil Does Not Improve Cardiomyopathy in Duchenne/Becker Muscular Dystrophy

OBJECTIVE: Duchenne and Becker muscular dystrophy (DBMD) are allelic disorders caused by mutations in dystrophin. Adults with DBMD develop life-threatening cardiomyopathy. Inhibition of phosphodiesterase 5 (PDE5) improves cardiac function in mouse models of DBMD. To determine if the PDE5-inhibitor s...

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書誌詳細
主要な著者: Leung, Doris G., Herzka, Daniel A., Thompson, W. Reid, He, Bing, Bibat, Genila, Tennekoon, Gihan, Russell, Stuart D., Schuleri, Karl H., Lardo, Albert C., Kass, David A., Thompson, Richard E., Judge, Daniel P., Wagner, Kathryn R.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191982/
https://ncbi.nlm.nih.gov/pubmed/25042693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24214
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