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Dominant Sequences of Human Major Histocompatibility Complex Conserved Extended Haplotypes from HLA-DQA2 to DAXX

We resequenced and phased 27 kb of DNA within 580 kb of the MHC class II region in 158 population chromosomes, most of which were conserved extended haplotypes (CEHs) of European descent or contained their centromeric fragments. We determined the single nucleotide polymorphism and deletion-insertion...

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Autores principales: Larsen, Charles E., Alford, Dennis R., Trautwein, Michael R., Jalloh, Yanoh K., Tarnacki, Jennifer L., Kunnenkeri, Sushruta K., Fici, Dolores A., Yunis, Edmond J., Awdeh, Zuheir L., Alper, Chester A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191933/
https://ncbi.nlm.nih.gov/pubmed/25299700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004637
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