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Escherichia coli iron superoxide dismutase targeted to the mitochondria of yeast cells protects the cells against oxidative stress.

A gene encoding a fusion protein consisting of Escherichia coli iron superoxide dismutase (FeSOD) with the mitochondrial targeting presequence of yeast manganese superoxide dismutase (MnSOD) was cloned and expressed in E. coli and in Saccharomyces cerevisiae DL1Mn- yeast cells deficient in MnSOD. In...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Balzan, R, Bannister, W H, Hunter, G J, Bannister, J V
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1995
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41915/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7753785/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.10.4219
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