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What makes the lac-pathway switch: identifying the fluctuations that trigger phenotype switching in gene regulatory systems

Multistable gene regulatory systems sustain different levels of gene expression under identical external conditions. Such multistability is used to encode phenotypic states in processes including nutrient uptake and persistence in bacteria, fate selection in viral infection, cell-cycle control and d...

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Autors principals: Bhogale, Prasanna M., Sorg, Robin A., Veening, Jan-Willem, Berg, Johannes
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191413/
https://ncbi.nlm.nih.gov/pubmed/25245949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku839
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