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Transmembrane protein 106A is silenced by promoter region hypermethylation and suppresses gastric cancer growth by inducing apoptosis

Inactivation of tumour suppressor genes by promoter methylation plays an important role in the initiation and progression of gastric cancer (GC). Transmembrane 106A gene (TMEM106A) encodes a novel protein of previously unknown function. This study analysed the biological functions, epigenetic change...

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Detalhes bibliográficos
Main Authors: Xu, Dong, Qu, Liujing, Hu, Jia, Li, Ge, Lv, Ping, Ma, Dalong, Guo, Mingzhou, Chen, Yingyu
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190911/
https://ncbi.nlm.nih.gov/pubmed/24975047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12352
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