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Molecular Dynamics Simulations of Galectin-1-oligosaccharide Complexes Reveal the Molecular Basis for Ligand Diversity

Galectin-1 is a member of a protein family historically characterized by its ability to bind carbohydrates containing a terminal galactosyl residue. Galectin-1 is found in a variety of mammalian tissues as a homodimer of 14.5-kDa subunits. A number of developmental and regulatory processes have been...

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Main Authors: Ford, Michael G., Weimar, Thomas, Köhli, Thies, Woods, Robert J.
格式: Artigo
語言:Inglês
出版: 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190840/
https://ncbi.nlm.nih.gov/pubmed/14517974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.10428
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