Nucleotide-oligomerizing domain-1 (NOD1) receptor activation induces pro-inflammatory responses and autophagy in human alveolar macrophages

BACKGROUND: Nucleotide-binding oligomerizing domain-1 (NOD1) is a cytoplasmic receptor involved in recognizing bacterial peptidoglycan fragments that localize to the cytosol. NOD1 activation triggers inflammation, antimicrobial mechanisms and autophagy in both epithelial cells and murine macrophages...

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Bibliographische Detailangaben
Hauptverfasser: Juárez, Esmeralda, Carranza, Claudia, Hernández-Sánchez, Fernando, Loyola, Elva, Escobedo, Dante, León-Contreras, Juan Carlos, Hernández-Pando, Rogelio, Torres, Martha, Sada, Eduardo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190423/
https://ncbi.nlm.nih.gov/pubmed/25253572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-14-152
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