Nuclear Ep-ICD accumulation predicts aggressive clinical course in early stage breast cancer patients

BACKGROUND: Regulated intramembrane proteolysis of Epithelial cell adhesion molecule (EpCAM) results in release of its intracellular domain (Ep-ICD) which triggers oncogenic signalling. The clinical significance of Ep-ICD in breast cancer remains to be determined. Herein, we examined the expression...

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Bibliografski detalji
Glavni autori: Srivastava, Gunjan, Assi, Jasmeet, Kashat, Lawrence, Matta, Ajay, Chang, Martin, Walfish, Paul G, Ralhan, Ranju
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190296/
https://ncbi.nlm.nih.gov/pubmed/25265904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-726
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