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Role of iron, zinc and reduced glutathione in oxidative stress induction by low pH in rat brain synaptosomes

Brain ischemia leads to a decrease in pH(o). We have shown previously in synaptosomes that the extracellular acidification induces depolarization of mitochondria followed by synthesis of superoxide anions and oxidative stress. Here, we investigated the effects of lowered pH(o) on oxidative stress an...

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Bibliographic Details
Main Authors: Pekun, Tatyana G, Hrynevich, Sviatlana V, Waseem, Tatyana V, Fedorovich, Sergei V
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190190/
https://ncbi.nlm.nih.gov/pubmed/25332861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-3-560
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