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Role of iron, zinc and reduced glutathione in oxidative stress induction by low pH in rat brain synaptosomes

Brain ischemia leads to a decrease in pH(o). We have shown previously in synaptosomes that the extracellular acidification induces depolarization of mitochondria followed by synthesis of superoxide anions and oxidative stress. Here, we investigated the effects of lowered pH(o) on oxidative stress an...

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Autors principals: Pekun, Tatyana G, Hrynevich, Sviatlana V, Waseem, Tatyana V, Fedorovich, Sergei V
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190190/
https://ncbi.nlm.nih.gov/pubmed/25332861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-3-560
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