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Acylation in trypanosomatids: an essential process and potential drug target

Fatty acylation—the addition of fatty acid moieties such as myristate and palmitate to proteins—is essential for the survival, growth, and infectivity of the trypanosomatids: Trypanosoma brucei, Trypanosoma cruzi, and Leishmania. Myristoylation and palmitoylation are critical for parasite growth, ta...

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Detalhes bibliográficos
Main Authors: Goldston, Amanda M., Sharma, Aabha I., Paul, Kimberly S., Engman, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190163/
https://ncbi.nlm.nih.gov/pubmed/24954795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pt.2014.05.003
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