Alternatively Spliced Tissue Factor Promotes Plaque Angiogenesis Through the Activation of HIF-1α and VEGF Signaling

BACKGROUND: Alternatively Spliced Tissue Factor (asTF) is a novel isoform of full-length Tissue Factor (fl-TF) that exhibits angiogenic activity. Although asTF has been detected in human plaques, it is unknown whether its expression in atherosclerosis causes increased neovascularization and an advan...

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Autores principales: Giannarelli, Chiara, Alique, Matilde, Rodriguez, David T., Yang, Dong Kwon, Jeong, Dongtak, Calcagno, Claudia, Hutter, Randolph, Millon, Antoine, Kovacic, Jason C., Weber, Thomas, Faries, Peter L., Soff, Gerald A., Fayad, Zahi A., Hajjar, Roger J., Fuster, Valentin, Badimon, Juan J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190117/
https://ncbi.nlm.nih.gov/pubmed/25116956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.006614
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