Generalized Functional Linear Models for Gene-based Case-Control Association Studies

By using functional data analysis techniques, we developed generalized functional linear models for testing association between a dichotomous trait and multiple genetic variants in a genetic region while adjusting for covariates. Both fixed and mixed effect models are developed and compared. Extensi...

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Hauptverfasser: Fan, Ruzong, Wang, Yifan, Mills, James L., Carter, Tonia C., Lobach, Iryna, Wilson, Alexander F., Bailey-Wilson, Joan E., Weeks, Daniel E., Xiong, Momiao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189986/
https://ncbi.nlm.nih.gov/pubmed/25203683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21840
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