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An assay for clogging the ciliary pore complex distinguishes mechanisms of cytosolic and membrane protein entry

As a cellular organelle, the cilium contains a unique protein composition [1, 2]. Entry of both membrane [3–5] and cytosolic components [6–8] is tightly regulated by gating mechanisms at the cilium base, however, the mechanistic details of ciliary gating are largely unknown. We previously proposed t...

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Detalhes bibliográficos
Main Authors: Takao, Daisuke, Dishinger, John F, Kee, H Lynn, Pinskey, Justine M, Allen, Ben L, Verhey, Kristen J
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189977/
https://ncbi.nlm.nih.gov/pubmed/25264252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.08.012
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