Role of the Renin–Angiotensin System in the Pathogenesis of Intimal Hyperplasia: Therapeutic Potential for Prevention of Vein Graft Failure?

The saphenous vein remains the most widely used conduit for peripheral and coronary revascularization despite a high rate of vein graft failure. The most common cause of vein graft failure is intimal hyperplasia. No agents have been proven to be successful for the prevention of intimal hyperplasia i...

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Main Authors: Osgood, Michael J., Harrison, David G., Sexton, Kevin W., Hocking, Kyle M., Voskresensky, Igor V., Komalavilas, Padmini, Cheung-Flynn, Joyce, Guzman, Raul J., Brophy, Colleen M.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189806/
https://ncbi.nlm.nih.gov/pubmed/22445245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.avsg.2011.12.001
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