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The Role of the Blood-Brain Barrier in the Pathogenesis of Senile Plaques in Alzheimer's Disease

The accumulation of beta-amyloid [Aβ] within senile plaques [SP] is characteristic of these lesions in Alzheimer's disease. The accumulation of Aβ (42), in particular, in the superior temporal [ST] cortex may result from an inability of the blood brain barrier (BBB) to regulate the trans-endoth...

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Détails bibliographiques
Auteurs principaux: Provias, J., Jeynes, B.
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189524/
https://ncbi.nlm.nih.gov/pubmed/25309772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/191863
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