Mechanisms of tissue uptake and retention of paclitaxel-coated balloons: impact on neointimal proliferation and healing

BACKGROUND: The efficacy of paclitaxel-coated balloons (PCB) for restenosis prevention has been demonstrated in humans. However, the mechanism of action for sustained drug retention and biological efficacy following single-time drug delivery is still unknown. METHODS AND RESULTS: The pharmacokinetic...

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Detalhes bibliográficos
Main Authors: Granada, Juan F, Stenoien, Mark, Buszman, Piotr P, Tellez, Armando, Langanki, Dan, Kaluza, Greg L, Leon, Martin B, Gray, William, Jaff, Michael R, Schwartz, Robert S
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
Assuntos:
Interventional Cardiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189287/
https://ncbi.nlm.nih.gov/pubmed/25332821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/openhrt-2014-000117
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