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Engineered three-dimensional microfluidic device for interrogating cell-cell interactions in the tumor microenvironment

Stromal cells in the tumor microenvironment play a key role in the metastatic properties of a tumor. It is recognized that cancer-associated fibroblasts (CAFs) and endothelial cells secrete factors capable of influencing tumor cell migration into the blood or lymphatic vessels. We developed a microf...

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Главные авторы: Hockemeyer, K., Janetopoulos, C., Terekhov, A., Hofmeister, W., Vilgelm, A., Costa, Lino, Wikswo, J. P., Richmond, A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Institute of Physics 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189212/
https://ncbi.nlm.nih.gov/pubmed/25379090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4890330
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