Dysregulation of genome-wide gene expression and DNA methylation in abnormal cloned piglets

BACKGROUND: Epigenetic modifications (especially altered DNA methylation) resulting in altered gene expression may be one reason for development failure or abnormalities in cloned animals, but the underlying mechanism of the abnormal phenotype in cloned piglets remains unknown. Some cloned piglets i...

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Bibliographic Details
Main Authors: Li, Guanglei, Jia, Qitao, Zhao, Jianguo, Li, Xinyun, Yu, Mei, Samuel, Melissa S, Zhao, Shuhong, Prather, Randall S, Li, Changchun
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189204/
https://ncbi.nlm.nih.gov/pubmed/25253444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-811
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