Effect of melatonin on incidence of delirium among patients with hip fracture: a multicentre, double-blind randomized controlled trial

BACKGROUND: Disturbance of the sleep–wake cycle is a characteristic of delirium. In addition, changes in melatonin rhythm influence the circadian rhythm and are associated with delirium. We compared the effect of melatonin and placebo on the incidence and duration of delirium. METHODS: We performed...

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Bibliografische gegevens
Hoofdauteurs: de Jonghe, Annemarieke, van Munster, Barbara C., Goslings, J. Carel, Kloen, Peter, van Rees, Carolien, Wolvius, Reinder, van Velde, Romuald, Levi, Marcel, de Haan, Rob J., de Rooij, Sophia E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Canadian Medical Association 2014
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188685/
https://ncbi.nlm.nih.gov/pubmed/25183726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/cmaj.140495
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