Effect of melatonin on incidence of delirium among patients with hip fracture: a multicentre, double-blind randomized controlled trial

BACKGROUND: Disturbance of the sleep–wake cycle is a characteristic of delirium. In addition, changes in melatonin rhythm influence the circadian rhythm and are associated with delirium. We compared the effect of melatonin and placebo on the incidence and duration of delirium. METHODS: We performed...

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Detalhes bibliográficos
Main Authors: de Jonghe, Annemarieke, van Munster, Barbara C., Goslings, J. Carel, Kloen, Peter, van Rees, Carolien, Wolvius, Reinder, van Velde, Romuald, Levi, Marcel, de Haan, Rob J., de Rooij, Sophia E.
Formato: Artigo
Idioma:Inglês
Publicado em: Canadian Medical Association 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188685/
https://ncbi.nlm.nih.gov/pubmed/25183726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/cmaj.140495
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