Serum Levels of Caspase-Cleaved Cytokeratin-18 and Mortality Are Associated in Severe Septic Patients: Pilot Study

OBJECTIVE: Apoptosis is increased in sepsis. Cytokeratin 18 (CK-18), a protein of the intermediate filament group present in most epithelial and parenchymal cells, is cleaved by the action of caspases and released into the blood as caspase-cleaved CK (CCCK)-18 during apoptosis. Circulating levels of...

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Main Authors: Lorente, Leonardo, Martín, María M., González-Rivero, Agustín F., Ferreres, José, Solé-Violán, Jordi, Labarta, Lorenzo, Díaz, César, Jiménez, Alejandro, Borreguero-León, Juan M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188625/
https://ncbi.nlm.nih.gov/pubmed/25290885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109618
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