Genetically Engineered Lactococcus lactis Protect against House Dust Mite Allergy in a BALB/c Mouse Model

BACKGROUND: Mucosal vaccine based on lactic acid bacteria is an attractive concept for the prevention and treatment of allergic diseases, but their mechanisms of action in vivo are poorly understood. Therefore, we sought to investigate how recombinant major dust mite allergen Der p2-expressing Lacto...

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Detalhes bibliográficos
Main Authors: Ai, Chunqing, Zhang, Qiuxiang, Ren, Chengcheng, Wang, Gang, Liu, Xiaoming, Tian, Fengwei, Zhao, Jianxin, Zhang, Hao, Chen, Yong Q., Chen, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188596/
https://ncbi.nlm.nih.gov/pubmed/25290938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109461
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