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A cAMP-Dependent, Protein Kinase A-Independent Signaling Pathway Mediating Neuritogenesis through Egr1 in PC12 Cells

The neurotrophic peptide PACAP (pituitary adenylate cyclase-activating polypeptide) elevates cAMP in PC12 cells. Forskolin and dibutyryl cAMP mimic PACAP’s neuritogenic and cell morphological effects, suggesting that they are driven by cAMP. Comparison of microarray expression profiles after exposur...

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Autors principals: Ravni, Aurélia, Vaudry, David, Gerdin, Matthew J., Eiden, Maribeth V., Falluel-Morel, Anthony, Gonzalez, Bruno J., Vaudry, Hubert, Eiden, Lee E.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188547/
https://ncbi.nlm.nih.gov/pubmed/18362103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.107.044792
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