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The bigger picture of FTO – the first GWAS-identified obesity gene

In 2007, SNPs that cluster in the first intron of FTO showed highly significant association in the first two genome-wide association studies for obesity traits of which the minor allele increases body mass index (BMI) by 0.39 kg/m(2) (or 1,130 g in body weight) and risk of obesity by 1.20 fold. Subs...

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Sonraí Bibleagrafaíochta
Main Authors: Loos, Ruth J.F., Yeo, Giles S.H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188449/
https://ncbi.nlm.nih.gov/pubmed/24247219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrendo.2013.227
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