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Identification of Amino Acid Epimerization and Isomerization in Crystallin Proteins by Tandem LC-MS
[Image: see text] Post-translational modifications that do not result in a change in mass are particularly difficult to detect by mass spectrometry. For example, isomerization of aspartic acid or epimerization of any chiral residue within a peptide do not lead to mass shifts but can be identified by...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American
Chemical
Society
2014
|
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4188265/ https://ncbi.nlm.nih.gov/pubmed/25188914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac502296c |
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