Complement Regulatory Protein CD46 Protects against Choroidal Neovascularization in Mice

Dysregulation of the complement system is increasingly recognized as a contributing factor in age-related macular degeneration. Although the complement regulator CD46 is expressed ubiquitously in humans, in mouse it was previously thought to be expressed only on spermatozoa. We detected CD46 mRNA an...

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Main Authors: Lyzogubov, Valeriy, Wu, Xiaobo, Jha, Purushottam, Tytarenko, Ruslana, Triebwasser, Michael, Kolar, Grant, Bertram, Paula, Bora, Puran S., Atkinson, John P., Bora, Nalini S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2014
Teme:
Immunopathology and Infectious Diseases
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188132/
https://ncbi.nlm.nih.gov/pubmed/25019227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.06.001
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