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Crystallization and preliminary X-ray diffraction analysis of a novel sphingomyelinase D from Loxosceles gaucho venom

Brown spider envenomation results in dermonecrosis, intravascular coagulation, haemolysis and renal failure, mainly owing to the action of sphingomyelinases D (SMases D), which catalyze the hydrolysis of sphingomyelin to produce ceramide 1-phosphate and choline or the hydrolysis of lysophosphatidylc...

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Detalhes bibliográficos
Main Authors: Ullah, Anwar, Magalhães, Geraldo Santana, Masood, Rehana, Mariutti, Ricardo Barros, Coronado, Monika Aparecida, Murakami, Mário Tyago, Barbaro, Katia Cristina, Arni, Raghuvir Krishnaswamy
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188093/
https://ncbi.nlm.nih.gov/pubmed/25286953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14019207
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