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Bioactive Lysophospholipids Generated by Hepatic Lipase Degradation of Lipoproteins Lead to Complement Activation via the Classical Pathway

PURPOSE. We determined bioactivity of lysophospholipids generated by degradation of the low-density (LDL), very low-density (VLDL), and high-density (HDL) lipoproteins with hepatic lipase (HL), cholesterol esterase (CE), and lipoprotein-associated phospholipase A2 (Lp-PLA2). METHODS. The LDL, VLDL,...

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Hlavní autoři: Ma, Wanchao, Paik, David C., Barile, Gaetano R.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188046/
https://ncbi.nlm.nih.gov/pubmed/25205869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14352
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