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Preferential effect of isoflurane on top-down vs. bottom-up pathways in sensory cortex

The mechanism of loss of consciousness (LOC) under anesthesia is unknown. Because consciousness depends on activity in the cortico-thalamic network, anesthetic actions on this network are likely critical for LOC. Competing theories stress the importance of anesthetic actions on bottom-up “core” thal...

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Autors principals: Raz, Aeyal, Grady, Sean M., Krause, Bryan M., Uhlrich, Daniel J., Manning, Karen A., Banks, Matthew I.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188029/
https://ncbi.nlm.nih.gov/pubmed/25339873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsys.2014.00191
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