The New Pyrazolyltetrazole Derivative MSN20 Is Effective via Oral Delivery against Cutaneous Leishmaniasis

An orally delivered, safe and effective treatment for leishmaniasis is an unmet medical need. Azoles and the pyrazolylpyrimidine allopurinol present leishmanicidal activity, but their clinical efficacies are variable. Here, we describe the activity of the new pyrazolyltetrazole hybrid, 5-[5-amino-1-...

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Autors principals: Faiões, Viviane dos Santos, dos Santos, Maurício Silva, Bernardino, Alice Maria Rolim, Cunha-Júnior, Edézio Ferreira, do Canto Cavalheiro, Marilene Marcuzzo, Torres-Santos, Eduardo Caio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187983/
https://ncbi.nlm.nih.gov/pubmed/25092697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02874-14
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