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In Vivo Effect of Quaternized Chitosan-Loaded Polymethylmethacrylate Bone Cement on Methicillin-Resistant Staphylococcus epidermidis Infection of the Tibial Metaphysis in a Rabbit Model

Infection of open tibial fractures with contamination remains a challenge for orthopedic surgeons. Local use of antibiotic-impregnated polymethylmethacrylate (PMMA) beads and blocks is a widely used procedure to reduce the risk of infection. However, the development of antibiotic-resistant organisms...

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Detalhes bibliográficos
Main Authors: Tan, Hong-lue, Ao, Hai-yong, Ma, Rui, Lin, Wen-tao, Tang, Ting-ting
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187961/
https://ncbi.nlm.nih.gov/pubmed/25070107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03489-14
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