Identification of a Novel 6′-N-Aminoglycoside Acetyltransferase, AAC(6′)-Iak, from a Multidrug-Resistant Clinical Isolate of Stenotrophomonas maltophilia

Stenotrophomonas maltophilia IOMTU250 has a novel 6′-N-aminoglycoside acetyltransferase-encoding gene, aac(6′)-Iak. The encoded protein, AAC(6′)-Iak, consists of 153 amino acids and has 86.3% identity to AAC(6′)-Iz. Escherichia coli transformed with a plasmid containing aac(6′)-Iak exhibited decreas...

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Hlavní autoři: Tada, Tatsuya, Miyoshi-Akiyama, Tohru, Dahal, Rajan K., Mishra, Shyam K., Shimada, Kayo, Ohara, Hiroshi, Kirikae, Teruo, Pokhrel, Bharat M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187913/
https://ncbi.nlm.nih.gov/pubmed/25092711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03354-14
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