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Inhibition of Cyclooxygenase-1 and Cyclooxygenase-2 Impairs Trypanosoma cruzi Entry into Cardiac Cells and Promotes Differential Modulation of the Inflammatory Response

The intracellular protozoan parasite Trypanosoma cruzi is the etiologic agent of Chagas disease, a serious disorder that affects millions of people in Latin America. Cell invasion by T. cruzi and its intracellular replication are essential to the parasite's life cycle and for the development of...

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Autores principales: Malvezi, Aparecida D., Panis, Carolina, da Silva, Rosiane V., de Freitas, Rafael Carvalho, Lovo-Martins, Maria I., Tatakihara, Vera L. H., Zanluqui, Nágela G., Neto, Edecio Cunha, Goldenberg, Samuel, Bordignon, Juliano, Yamada-Ogatta, Sueli F., Martins-Pinge, Marli C., Cecchini, Rubens, Pinge-Filho, Phileno
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187892/
https://ncbi.nlm.nih.gov/pubmed/25092706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02752-14
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