Intestinal Epithelium-Specific MyD88 Signaling Impacts Host Susceptibility to Infectious Colitis by Promoting Protective Goblet Cell and Antimicrobial Responses

Intestinal epithelial cells (IECs), including secretory goblet cells, form essential physiochemical barriers that separate luminal bacteria from underlying immune cells in the intestinal mucosa. IECs are common targets for enteric bacterial pathogens, with hosts responding to these microbes through...

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Main Authors: Bhinder, Ganive, Stahl, Martin, Sham, Ho Pan, Crowley, Shauna M., Morampudi, Vijay, Dalwadi, Udit, Ma, Caixia, Jacobson, Kevan, Vallance, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Host Response and Inflammation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187802/
https://ncbi.nlm.nih.gov/pubmed/24958710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02045-14
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