Intestinal Epithelium-Specific MyD88 Signaling Impacts Host Susceptibility to Infectious Colitis by Promoting Protective Goblet Cell and Antimicrobial Responses

Intestinal epithelial cells (IECs), including secretory goblet cells, form essential physiochemical barriers that separate luminal bacteria from underlying immune cells in the intestinal mucosa. IECs are common targets for enteric bacterial pathogens, with hosts responding to these microbes through...

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Detalhes bibliográficos
Main Authors: Bhinder, Ganive, Stahl, Martin, Sham, Ho Pan, Crowley, Shauna M., Morampudi, Vijay, Dalwadi, Udit, Ma, Caixia, Jacobson, Kevan, Vallance, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187802/
https://ncbi.nlm.nih.gov/pubmed/24958710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02045-14
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