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Syk Interacts with and Phosphorylates Nucleolin To Stabilize Bcl-x(L) mRNA and Promote Cell Survival
The Syk protein tyrosine kinase, a well-characterized regulator of immune cell function, plays an increasingly recognized role in tumorigenesis as a promoter of cell survival in both hematological and nonhematological malignancies. We show here that the expression of Syk in MCF7 or MDA-MB-231 breast...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4187708/ https://ncbi.nlm.nih.gov/pubmed/25092868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00937-14 |
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