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Syk Interacts with and Phosphorylates Nucleolin To Stabilize Bcl-x(L) mRNA and Promote Cell Survival

The Syk protein tyrosine kinase, a well-characterized regulator of immune cell function, plays an increasingly recognized role in tumorigenesis as a promoter of cell survival in both hematological and nonhematological malignancies. We show here that the expression of Syk in MCF7 or MDA-MB-231 breast...

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Autores principales: Wang, Wen-Horng, Childress, Michael O., Geahlen, Robert L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187708/
https://ncbi.nlm.nih.gov/pubmed/25092868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00937-14
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